Big Mac Casserole

Big Mac Casserole

Healthy Fact of the Day

Ground beef provides essential protein and B vitamins for energy and muscle health. Using lean ground beef and adding extra vegetables can boost the nutritional value while maintaining that classic flavor.

July 1, 2025

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Big Mac Casserole

Big Mac Casserole

Recipe by Daily Disher

Big Mac Casserole brings together seasoned ground beef, melted cheddar cheese, pickle relish, and Thousand Island dressing over a bread base for burger bliss.

Course: Main

/

Cuisine: American

/

Difficulty: Easy

Servings

6

Prep time

15 minutes

Cooking time

40 minutes

Calories

500 kcal

55 minutes


Ingredients

1 pound ground beef

1 cup diced onions

2 cups shredded cheddar cheese

2 tablespoons pickle relish

1 cup thousand island dressing

4 cups cubed bread

1 teaspoon salt

½ teaspoon black pepper


Directions

1.

Preheat your oven to 350°F (175°C) and grease a 9x13-inch baking dish to prepare for baking.

2.

In a large skillet over medium heat, cook the ground beef and diced onions until the beef is browned, about 8-10 minutes.

3.

Drain any excess fat from the skillet and season the beef mixture with salt and black pepper.

4.

Spread the cubed bread evenly in the prepared baking dish to form the base layer of the casserole.

5.

Evenly distribute the cooked beef mixture over the layer of bread in the baking dish.

6.

Sprinkle the shredded cheddar cheese evenly over the beef to ensure consistent melting and flavor throughout.

7.

Drizzle the pickle relish and thousand island dressing evenly over the cheese layer for added taste.

8.

Bake in the preheated oven for 25-30 minutes until the cheese is bubbly and the top is golden brown.

9.

Allow the casserole to cool slightly before serving to ensure it holds its shape when sliced.


Nutrition Facts

Total number of serves:

4 servings

Calories:

500kcal

Cholesterol:

0mg

Sodium:

620mg

Potassium:

400mg

Sugar:

8g

Protein:

6g

Calcium:

60mg

Iron:

2mg

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This Big Mac Casserole captures all the beloved flavors of the iconic fast-food burger in a family-friendly casserole format that’s perfect for weeknight dinners. Seasoned ground beef mingles with tangy pickle relish and creamy Thousand Island dressing, while melted cheddar cheese creates that signature burger taste. Built on a foundation of cubed bread that soaks up all the delicious flavors, it’s comfort food that brings back childhood memories with every bite.

If you love creative takes on classic favorites like this, you’ll also enjoy our Cheesesteak Tortellini in Provolone Sauce with its similar comfort food appeal and cheese-forward flavors. For another crowd-pleasing casserole, try the Tamale Casserole, which transforms another beloved dish into an easy-to-serve family meal.

Can’t get enough of great flavors? Check out these popular recipes that readers love making again and again.

For hearty family favorites, our Hamburger Steak in Creamy Dill Sauce and Ground Turkey Sweet Potato Skillet deliver that perfect combination of satisfying protein and rich flavors. When you’re looking for more comfort food casseroles, the Green Chile Chicken and Rice Casserole and Smothered Pork Chop and Scalloped Potato Casserole bring warmth and convenience to your dinner table. Need quick weeknight solutions? Our Garlic Chicken with Broccoli and Spinach and Pineapple Chicken and Rice get dinner done fast without sacrificing flavor.

Browse our full collection for more kitchen inspiration that’ll have your family asking for seconds.

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